Drexel Biomedical Engineering Research Papers

Major: Biomedical Engineering
Degree Awarded: Master of Science (MS) or Doctor of Philosophy (PhD)
Calendar Type: Quarter
Total Credit Hours: 45.0-51.0 (MS) or 90.0 (PhD)
Co-op Option: Available for full-time on-campus master's-level students
Classification of Instructional Programs (CIP) code: 14.0501
Standard Occupational Classification (SOC) code: 17-2031

About the Program

The curriculum develops graduates who can identify and address unmet clinical, diagnostic, and healthcare needs by using their knowledge of modern theories, engineering systems, and mathematical and engineering tools. Biomedical engineers require the analytical tools and broad knowledge of modern engineering and science, fundamental understanding of the biological or physiological system, and familiarity with recent technological breakthroughs.

Master students can choose to include a 6 months graduate co-op cycle as part of their studies. Students may also choose to enroll in a concentration in Biomedical Device Development, or specialize inbiomaterials and tissue engineering, biomechanics, neuroengineering, imaging and devices or bioinformatics,or may pursue a dual-degree MS option. Graduating students work in industry in such fields as medical devices, health care, pharmaceuticals and biotechnology, continue academic careers (PhD), or continue to medical schools. 

Additional Information

Natalia Broz
Associate Director for Graduate Programs
School of Biomedical Engineering, Science and Health Systems
Email: njb33@drexel.edu

Andres Kriete, PhD
Associate Director for Graduate Studies
School of Biomedical Engineering, Science and Health Systems
Email: ak3652@drexel.edu

For more information, visit the The School of Biomedical Engineering, Science, and Health Systems website.

Degree Requirements (MS)

The core requirements for the master's in biomedical engineering encompass approximately 45.0 course credits (most courses carry three credits each). Students who choose the non-thesis option cannot register for thesis or research credits.

The curriculum includes room for specialization in several areas of biomedical engineering, as well as a concentration in biomedical technology development.

Biomedical Technology Development Concentration (Optional)

Students enrolled in this concentration will develop an understanding of critical regulatory, economic, and legal issues in addition to the project management skills that facilitate the development of new medical devices and positive working relationships with intellectual property lawyers, insurance companies, and the federal government.

BMES 509Entrepreneurship for Biomedical Engineering and Science3.0
BMES 534Design Thinking for Biomedical Engineers3.0
BMES 538Biomedical Ethics and Law3.0
BMES 588Medical Device Development3.0
BMES 596Clinical Practicum III3.0
Total Credits15.0

Biomaterials and Tissue Engineering Concentration (Optional)

This concentration is designed to provide students with advanced training in cellular and molecular biology relevant to tissue engineering and behavior of materials used in biomedical applications

Bioinformatics Concentration (Optional)

This concentration emphasizes a systems engineering approach to provide a foundation in systems biology and pathology informatics. Students are provided students with hands-on experience in the application of genomic, proteomic, and other large-scale information to biomedical engineering as well as experience in advanced computational methods used in systems biology: pathway and circuitry, feedback and control, cellular automata, sets of partial differential equations, stochastic analysis, and biostatistics.

BMES 543Quantitative Systems Biology4.0
BMES 544Genome Information Engineering4.0
BMES 547Machine Learning in Biomedical Applications3.0
or BMES 549 Genomic and Sequencing Technologies
BMES 551Biomedical Signal Processing3.0
BMES 604Pharmacogenomics3.0
Total Credits17.0

Sample Plan of Study (MS)

First Year
FallCredits
BMES 501Medical Sciences I3.0
BMES 510Biomedical Statistics4.0
BMES 546
or 550
Biocomputational Languages
Advanced Biocomputational Languages
4.0
BMES 864Seminar0.0
Term Credits11.0
Winter
BMES 502Medical Sciences II3.0
BMES 672Biosimulation I3.0
BMES 864Seminar0.0
BMES Elective3.0-4.0
Term Credits9.0-10.0
Spring
BMES 503Medical Sciences III3.0
BMES 673Biosimulation II3.0
BMES 538Biomedical Ethics and Law (can be taken in any term)3.0
BMES 864Seminar0.0
Term Credits9.0
Second Year
Fall
Elective Courses and/or Thesis*9.0-12.0
Term Credits9.0-12.0
Winter
Elective Courses and/or Thesis**7.0-12.0
Term Credits7.0-12.0
Total Credit: 45.0-54.0

PhD in Biomedical Engineering Degree Requirements

To be awarded the PhD degree, students must complete 90.0 required credits and fulfill the one-year residency requirement.
The following milestones have to be satisfied during the course of the program:

  • Students must successfully pass the candidacy examination.
  • Students must submit a PhD dissertation proposal and successfully defend it.
  • Students must write a dissertation and successfully pass final oral defense.

Post-Baccalaureate Requirements and Post-Master's Requirements
Both post-baccalaureate and post-master's students are admitted into the doctoral program in Biomedical Engineering, but have slightly differing sets of requirements.

For post-master’s students, 45.0 of the credits that they earned toward their Master’s degree may be applied toward the PhD. If coming from the Master’s program in Biomedical Engineering at Drexel University, those courses they took would apply. For non-Drexel students who have completed their master’s elsewhere, there may be exceptions made. If these students believe that they have covered the material of the required courses in another program, they must show evidence of such material and obtain a formal waiver of this requirement from the Graduate Advisor.

For post-baccalaureate students, students must complete a minimum of 90.0 credits and a research thesis. These 90.0 credits include the core courses required by Drexel’s MS in Biomedical Engineering.


In addition to the required courses, post-baccalaureate PhD students must take at least 21.0 more credits in courses. This balance may be taken as research and/or thesis/dissertation credits.

Thesis Advisor/Plan of Study
During the first year of the program all Doctoral students are required to identify a Thesis Advisor and complete a plan of study. The student’s Thesis Advisor and the Graduate Advisor will guide the student in developing this plan of study. Each plan of study is individually tailored to the student, and includes a combination of research and course credits most beneficial and complimentary to the student’s chosen thesis topic.

The Candidacy Examination
Doctoral students must successfully pass a candidacy examination, preferably at the end of the first year of their study.
The overall objective of the candidacy examination is to test the student's basic knowledge and preparedness to proceed toward a PhD in Biomedical Engineering. After a satisfactory performance on the candidacy examination the student is awarded the Doctoral Candidate status. Candidates must submit a Thesis Proposal by the end of the second year and defend it in an oral presentation to a committee of five faculty members.

Thesis Defense
After the student has successfully completed all the necessary research and composed a thesis manuscript, in accordance with the guidelines specified by the Office of Research and Graduate Studies, he or she then must formally defend their thesis. A formal thesis defense includes an oral presentation of research accomplishments in front of a committee of faculty members. The thesis defense is open to the general public.

Prospective PhD students are welcome to contact the school to discuss their research interests. For a more detailed description of the PhD requirements, please visit the School of Biomedical Engineering and Health Systems' Biomedical Engineering web site.

Areas of Specialization

Areas of specialization can be pursued within the Biomedical Engineering graduate program. Students can plan their own focus area that will give them strength in a particular sub-discipline. Alternatively, the student can specialize by conducting research and writing a thesis.

Biomaterials and Tissue Engineering
Biomaterials and tissue engineering is designed to provide students with advanced training in cellular and molecular biology relevant to tissue engineering and behavior of materials used in biomedical applications.

Biomedical Technology Development
Students pursuing the concentration will develop an understanding of critical regulatory, economic, and legal issues in addition to the project management skills that facilitate the development of new medical devices and positive working relationships with intellectual property lawyers, insurance companies, and the federal government. (This is a formal concentration with specific course requirements.)

Bioinformatics
Bioinformatics emphasizes a systems engineering approach to provide a foundation in systems biology and pathology informatics. Students are provided with hands-on experience in the application of genomic, proteomic, and other large-scale information to biomedical engineering as well as experience in advanced computational methods used in systems biology: pathway and circuitry, feedback and control, cellular automata, sets of partial differential equations, stochastic analysis, and biostatistics.

Biomechanics and Human Performance Engineering
Biomechanics and human performance engineering is designed to meet two objectives: to acquaint students with the responses of biological tissues to mechanical loads as well as with the mechanical properties of living systems and to provide students with the background and skills needed to create work and living environments which improve human health and enhance performance. Biomechanics and human performance also involves the study of orthopedic appliances and the broader aspect of rehabilitation engineering and the management of disability.

Biomedical Systems and Imaging
Biomedical systems and imaging focuses on the theoretical and practical issues related to machine vision, image processing and analysis, and signal processing associated with such medical applications as well biomedical instrumentation and product development.

Neuroengineering
Neuroengineering is broadly defined to include the modeling of neural and endocrine systems, neural networks, complexity in physiological systems, evolutionary influences in biological control systems, neurocontrol, neurorobotics, and neuroprosthetics.

Biomedical Engineering, Science and Health Systems Faculty

Fred D. Allen, PhD(University of Pennsylvania)Associate Director, Undergraduate Education. Assistant Professor. Tissue engineering, cell engineering, orthopedics, bone remodeling, wound healing, mechanotransduction, signal transduction, adhesion, migration.

Hasan Ayaz, PhD(Drexel University)School of Biomedical Engineering, Science and Health Systems. Research Associate Professor. Optical brain imaging, cognitive neuroengineering, brain computer interface (BCI), functional ner infrared (fNIR), and near infrared spectroscopy (NIRS).

Sriram Balasubramanian, PhD(Wayne State University). Assistant Professor. Structural characteristics of the pediatric thoracic cage using CT scans and developing an age-equivalent animal model for pediatric long bones.

Kenneth A. Barbee, PhD(University of Pennsylvania). Professor. Cellular biomechanics of neural and vascular injury, mechanotransduction in the cardiovascular system, mechanical control of growth and development for wound healing and tissue engineering.

Donald Buerk, PhD(Northwestern University). Research Professor. Biotechnology, physiology, systems biology, blood flow, microcirculation, nitric oxide, oxygen transport

Jamie Dougherty, PhD(Drexel University). Assistant Teaching Professor. Brain-computer interface, neural encoding, electrophysiological signal acquisition and processing.

Lin Han, PhD(Massachusetts Institute of Technology). Assistant Professor. Nanoscale structure-property relationships of biological materials, genetic and molecular origins soft joint tissue diseases, biomaterials under extreme conditions, coupling between stimulus-responsiveness and geometry.

Uri Hershberg, PhD(Hebrew University of Jerusalem, Israel). Assistant Professor. Bioinformatics, immunology, neural computation, system biology, somatic selection, autoimmunity, genetic stability, germline diversity, dendritic cell, transcription elements, pathogens, computational and mathematical modeling, complex systems, cognition and inflammation.

Kurtulus Izzetoglu, PhD(Drexel University)Associate Research Professor. Cognitive neuroengineering, functional brain imaging, near infrared spectroscopy, medical sensor development, biomedical signal processing, human performance assessment, and cognitive aging

Meltem Izzetoglu, PhD(Drexel University). Associate Research Professor. Cognitive neuroengineering, biomedical signal processing, statistical signal analysis, optimal artifact removal, information processing, optical brain imaging, functional near infrared spectroscopy, working memory, attention, learning, reading and mathematical disabilities, cognitive aging, anesthesia awareness, and social anxiety disorders.

Dov Jaron, PhD(University of Pennsylvania)Calhoun Distinguished Professor of Engineering in Medicine. Professor. Mathematical, computer and electromechanical simulations of the cardiovascular system.

Andres Kriete, PhD(University in Bremen Germany)Associate Director for Graduate Studies and Academic Operations. Systems biology, bioimaging, control theory, biology of aging, skin cancer.

Steven Kurtz, PhD(Cornell University). Associate Research Professor. Computational biomechanics of bone-implant systems and impact-related injuries, orthopaedic biomechanics, contact mechanics, orthopaedic biomaterials, large-deformation mechanical behavior and wear of polymers, and degradation and crosslinking of polyolefins in implant applications.

Ryszard Lec, PhD(University of Warsaw Engineering College). Professor. Biomedical applications of visoelastic, acoustoptic and ultrasonic properties of liquid and solid media.

Peter Lewin, PhD(University of Denmark, Copenhagen-Lyngby)Richard B. Beard Professor, School Of Biomedical Engineering, Science & Health Systems. Professor. Biomedical ultrasonics, piezoelectric and polymer transducers and hydrophones; shock wave sensors.

Hualou Liang, PhD(Chinese Academy of Sciences). Professor. Neuroengineering, neuroinformatics, cognitive and computational neuroscience, neural data analysis and computational modeling, biomedical signal processing.

Donald L. McEachron, PhD(University of California at San Diego)Coordinator, Academic Assessment and Improvement. Teaching Professor. Animal behavior, autoradiography, biological rhythms, cerebral metabolism, evolutionary theory, image processing, neuroendocrinology.

Karen Moxon, PhD(University of Colorado)Associate Director for Research. Professor. Cortico-thalamic interactions; neurobiological perspectives on design of humanoid robots.

Michael Neidrauer, PhD(Drexel University). Assistant Research Professor. Wound healing, near infrared, spectroscopy, cell culture, data analysis, optical coherence tomography (OCT), matlab, life sciences assay development, confocal microscopy, biomaterials, in-vivo, medical devices

Banu Onaral, PhD(University of Pennsylvania)H.H. Sun Professor; Senior Advisor to the President, Global Partnerships. Professor. Biomedical signal processing; complexity and scaling in biomedical signals and systems.

Kambiz Pourrezaei, PhD(Rensselaer Polytechnic University). Professor. Thin film technology; nanotechnology; near infrared imaging; power electronics.

Ahmet Sacan, PhD(Middle East Technical University). Assistant Professor. Indexing and data mining in biological databases; protein sequence and structure; similarity search; protein structure modeling; protein-protein interaction; automated cell tracking.

Joseph J. Sarver, PhD(Drexel University). Associate Professor. Neuromuscular adaptation to changes in the myo-mechanical environment.

Rahamim Seliktar, PhD(University of Strathclyde, Glasgow)Vice Director, School of Biomedical Engineering, Science & Health Systems. Professor. Limb prostheses, biomechanics of human motion, orthopedic biomechanics.

Patricia A. Shewokis, PhD(University of Georgia). Professor. Roles of cognition and motor function during motor skill learning; role of information feedback frequency on the memory of motor skills, noninvasive neural imaging techniques of functional near infrared spectroscopy(fNIR) and electroencephalograpy (EEG) and methodology and research design.

Adrian C. Shieh, PhD(Rice University). Assistant Professor. Contribution of mechanical forces to tumor invasion and metastasis, with a particular emphasis on how biomechanical signals may drive the invasive switch, and how the biomechanical microenvironment interacts with cytokine signaling and the extracellular matrix to influence tumor and stromal cell behavior.

Wan Y. Shih, PhD(Ohio State University). Associate Professor. Piezoelectric microcantilever biosensors development, piezoelectric finger development, quantum dots development, tissue elasticity imaging, piezoelectric microcantilever force probes.

Kara Spiller, PhD(Drexel University). Assistant Professor. Macrophage-biometerial interactions, drug delivery systems, and chronic would healing. Cell-biomaterial interactions, biomaterial design, and international engineering education.

Marek Swoboda, PhD(Drexel University). Assistant Teaching Professor. Cardiovascular engineering, cardiovascular system, diagnostic devices in cardiology, piezoelectric biosensors, and pathogen detection.

Amy Throckmorton, PhD(University of Virginia). Associate Professor. Computational and experimental fluid dynamics; cardiovascular modeling, including transient, fluid-structure interaction, and patient-specific anatomical studies; bench-to-bedside development of medical devices; artificial organs research; prediction and quantification of blood trauma and thrombosis in medical devices; design of therapeutic alternatives for patients with dysfunctional single ventricle physiology; human factors engineering of mechanical circulatory assist devices

Margaret Wheatley, PhD(University of Toronto)John M. Reid Professor. Ultrasound contrast agent development (tumor targeting and triggered drug delivery), controlled release technology (bioactive compounds), microencapsulated allografts (<em>ex vivo </em> gene therapy) for spinal cord repair.

Ming Xiao, PhD(Baylor University). Associate Professor. Nanotechnology, single molecule detection, single molecule fluorescent imaging, genomics, genetics, genome mapping, DNA sequencing, DNA biochemistry, and biophysics.

Yinghui Zhong, PhD(Georgia Institute of Technology). Assistant Professor. Spinal cord repair, and engineering neural prosthesis/brain interface using biomaterials, drug delivery, and stem cell therapy.

Leonid Zubkov, PhD, DSc(St. Petersburg State University, Russia). Research Professor. Physiology, wound healing, physiologic neovascularization, near-infrared spectroscopy, optical tomography, histological techniques, computer-assisted diagnosis, infrared spectrophotometry, physiologic monitoring, experimental diabetes mellitus, penetrating wounds, diabetes complications, skin, animal models, radiation scattering, failure analysis

Catherin von Reyn, PhD(University of Pennsylvania). Assistant Professor. Cell type-specific genetic engineering, whole-cell patch clamp in behaving animals, modeling, and detailed behavioral analysis to identify and characterize sensorimotor circuits.

Emeritus Faculty

Hun H. Sun, PhD (Cornell University). Professor Emeritus. Biological control systems, physiological modeling, systems analysis.

Major: Biomedical Engineering: Biomaterials and Tissue Engineering Concentration
Degree Awarded: Bachelor of Science
Calendar Type: Quarter
Total Credit Hours: 198.5
Co-op Options: Three Co-op (Five years); One Co-op (Four years)
Classification of Instructional Programs (CIP) code: 14.0501
Standard Occupational Classification (SOC) code:
17-2031

About the Program

The biomaterials and tissue engineering concentration focuses on the fundamental knowledge of natural and synthetic biomaterials and cellular biology and educates students in the emerging field of cellular and tissue engineering. 

The concentration in biomaterials and tissue engineering includes courses from the Departments of Biology, Chemistry, and Mechanical Engineering & Mechanics. The program builds on the fundamental knowledge of natural and synthetic biomaterials and cellular biology and educates students in the emerging field of cellular and tissue engineering.

Biomaterials research has recently expanded to include fibrous materials and various prosthetic devices requiring the use of both synthetic and natural fibers. The emphasis is on improved materials and design of biological replacement tissues through cellular tissue engineering.
Upon graduation, students will be able to:

  • select and evaluate biomaterials for use in biomedical applications in vivo;
  • develop in vitro models for drug delivery, drug toxicity and drug discovery choosing the appropriate biomaterials;
  • create high-fidelity tissue models in vitro;
  • develop and evaluate tissue engineering approaches to initiate and promote regenerative processes in vivo.

The School maintains extensive facilities and laboratories devoted to areas of research. Visit the School's BIOMED Research Facilities and Laboratory Map web page for more details about the laboratories and equipment available.

For more information about this concentration, see Drexel's School of Biomedical Engineering, Science, and Health Systems web site.

Degree Requirements

HIST 285Technology in Historical Perspective4.0
ENGL 101Composition and Rhetoric I: Inquiry and Exploratory Research3.0
ENGL 102Composition and Rhetoric II: Advanced Research and Evidence-Based Writing3.0
ENGL 103Composition and Rhetoric III: Themes and Genres3.0
CIVC 101Introduction to Civic Engagement1.0
UNIV R101The Drexel Experience1.0
*15.0
MATH 121Calculus I4.0
MATH 122Calculus II4.0
MATH 200Multivariate Calculus4.0
PHYS 101Fundamentals of Physics I4.0
PHYS 102Fundamentals of Physics II4.0
PHYS 201Fundamentals of Physics III4.0
CHEM 101General Chemistry I3.5
CHEM 102General Chemistry II4.5
BIO 122Cells and Genetics4.5
ENGR 100Beginning Computer Aided Drafting for Design1.0
ENGR 101Engineering Design Laboratory I2.0
ENGR 102Engineering Design Laboratory II2.0
ENGR 103Engineering Design Laboratory III2.0
ENGR 121Computation Lab I2.0
ENGR 122Computation Lab II1.0
ENGR 210Introduction to Thermodynamics3.0
ENGR 220Fundamentals of Materials4.0
ENGR 231Linear Engineering Systems3.0
ENGR 232Dynamic Engineering Systems3.0
MEM 202Statics3.0
BIO 201Human Physiology I4.0
BIO 203Human Physiology II4.0
BMES 124Biomedical Engineering Freshman Seminar I1.0
BMES 126Biomedical Engineering Freshman Seminar II1.0
BMES 130Problem Solving in Biomedical Engineering2.0
BMES 201Programming and Modeling for Biomedical Engineers I3.0
BMES 202Programming and Modeling for Biomedical Engineers ll3.0
BMES 212The Body Synthetic3.0
BMES 302Laboratory II: Biomeasurements2.0
BMES 303Laboratory III: Biomedical Electronics2.0
BMES 310Biomedical Statistics4.0
BMES 325Principles of Biomedical Engineering I3.0
BMES 326Principles of Biomedical Engineering II3.0
BMES 338Biomedical Ethics and Law3.0
BMES 372Biosimulation3.0
BMES 381Junior Design Seminar I2.0
BMES 382Junior Design Seminar II2.0
BMES 491 [WI] Senior Design Project I3.0
BMES 492Senior Design Project II2.0
BMES 493Senior Design Project III3.0
ECE 201Foundations of Electric Circuits3.0
BIO 218Principles of Molecular Biology4.0
BIO 219 [WI] Techniques in Molecular Biology3.0
BMES 345Mechanics of Biological Systems3.0
BMES 375Computational Bioengineering4.0
BMES 451Transport Phenomena in Living Systems4.0
BMES 460Biomaterials I4.0
BMES 461Biomaterials II4.0
BMES 471Cellular and Molecular Foundations of Tissue Engineering4.0
BMES 472Developmental and Evolutionary Foundations of Tissue Engineering4.0
BMES 475Biomaterials and Tissue Engineering III4.0
CHEM 241Organic Chemistry I4.0
CHEM 242Organic Chemistry II4.0
4.0

BMES 301

Laboratory I: Experimental Biomechanics (2cr)

BMES 304

Laboratory IV: Ultrasound Images (2cr)

BIO 202

Human Physiology Laboratory (2cr)

CHEM 244

Organic Chemistry Laboratory I (3cr)

CHEM 245

Organic Chemistry Laboratory II (3cr)
Total Credits198.5

Writing-Intensive Course Requirements

In order to graduate, all students must pass three writing-intensive courses after their freshman year. Two writing-intensive courses must be in a student's major. The third can be in any discipline. Students are advised to take one writing-intensive class each year, beginning with the sophomore year, and to avoid “clustering” these courses near the end of their matriculation. Transfer students need to meet with an academic advisor to review the number of writing-intensive courses required to graduate.

A "WI" next to a course in this catalog may indicate that this course can fulfill a writing-intensive requirement. For the most up-to-date list of writing-intensive courses being offered, students should check the Writing Intensive Course List at the University Writing Program. Students scheduling their courses can also conduct a search for courses with the attribute "WI" to bring up a list of all writing-intensive courses available that term.

Opportunities

Metropolitan Philadelphia has one of the highest concentrations of medical institutions and pharmaceutical and biotechnology industries in the nation. The bachelor of science degree in biomedical engineering gives students access to a broad spectrum of career opportunities in medical device and equipment industry; prosthetics and assist devices industry; biomaterials and implants industry; and the telemedicine, pharmaceutical, biotechnology, and agricultural sectors.

Biomedical engineering graduates are also ideally prepared for professional education in medicine, dentistry, veterinary medicine, and law. Those who choose to pursue graduate education can aim for careers in research and development, biomedical technology innovation and transfer, as well as health care technology management.

Visit the Drexel Steinbright Career Development Center page for more detailed information on co-op and post-graduate opportunities.

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